(2023-01-28). [Comment] Developing a vaccine against Marburg virus disease. thelancet.com Marburg virus disease is a severe infection in people and non-human primates (NHPs), with a case-fatality rate of 23—90%.1 The disease is caused by the Marburg virus, a member of the Filoviridae family, which includes the viruses responsible for Ebola virus disease.1 Marburg virus disease is extremely rare. Since its discovery in 1967, when two outbreaks occurred simultaneously in laboratories in Marburg and Frankfurt in Germany, and in Belgrade, Yugoslavia (now Serbia), causing 31 cases and seven deaths, there have been 16 known outbreaks with a cumulative total of fewer than 500 reported cases.
(2023-01-28). [Articles] Safety, tolerability, and immunogenicity of the chimpanzee adenovirus type 3-vectored Marburg virus (cAd3-Marburg) vaccine in healthy adults in the USA: a first-in-human, phase 1, open-label, dose-escalation trial. thelancet.com This first-in-human trial of this cAd3-Marburg vaccine showed the agent is safe and immunogenic, with a safety profile similar to previously tested cAd3-vectored filovirus vaccines. 95% of participants produced a glycoprotein-specific antibody response at 4 weeks after a single vaccination, which remained in 70% of participants at 48 weeks. These findings represent a crucial step in the development of a vaccine for emergency deployment against a re-emerging pathogen that has recently expanded its reach to new regions.
(2023-01-28). [Comment] Developing a vaccine against Marburg virus disease. thelancet.com Marburg virus disease is a severe infection in people and non-human primates (NHPs), with a case-fatality rate of 23—90%.1 The disease is caused by the Marburg virus, a member of the Filoviridae family, which includes the viruses responsible for Ebola virus disease.1 Marburg virus disease is extremely rare. Since its discovery in 1967, when two outbreaks occurred simultaneously in laboratories in Marburg and Frankfurt in Germany, and in Belgrade, Yugoslavia (now Serbia), causing 31 cases and seven deaths, there have been 16 known outbreaks with a cumulative total of fewer than 500 reported cases.
(2023-01-28). [Articles] Safety, tolerability, and immunogenicity of the chimpanzee adenovirus type 3-vectored Marburg virus (cAd3-Marburg) vaccine in healthy adults in the USA: a first-in-human, phase 1, open-label, dose-escalation trial. thelancet.com This first-in-human trial of this cAd3-Marburg vaccine showed the agent is safe and immunogenic, with a safety profile similar to previously tested cAd3-vectored filovirus vaccines. 95% of participants produced a glycoprotein-specific antibody response at 4 weeks after a single vaccination, which remained in 70% of participants at 48 weeks. These findings represent a crucial step in the development of a vaccine for emergency deployment against a re-emerging pathogen that has recently expanded its reach to new regions.
(2023-01-28). WHO considers 'global emergency' status. ecns.cn The World Health Organization's emergency committee was due to meet on Friday to evaluate whether the COVID-19 pandemic still represents a global emergency.
(2023-01-28). Outbreak of avian flu has killed more than 100 million birds and poses a serious threat of becoming a human pandemic. wsws.org Since October 2021, the spread of the H5N1 highly pathogenic avian flu among birds in North America and Europe has killed more than 140 million poultry and wild birds through disease and culling. The spread of the virus at a mink farm in Spain raises immediate concern about the nature of the mutation the current clade of the virus possesses and its threat to human populations.
(2023-01-28). Herd immunity impedes spread of COVID-19 in China: expert. ecns.cn With most people in China having been infected with COVID-19, herd immunity has been reached and the transmission ability of the epidemic gradually weakens, said Fang Bangjiang, a doctor from Longhua Hospital Affiliated with Shanghai University of Traditional Chinese Medicine, on Friday.
(2023-01-28). Nation sees therapeutics success. ecns.cn China will create broad-spectrum treatments to tackle mutated strains of the COVID-19 virus and develop drugs with novel mechanisms to fight the pathogen, according to a document provided to China Daily.
(2023-01-28). Millions on journeys as break nears end. ecns.cn Halfway through the Spring Festival travel rush, the anticipated passenger flow surge has demonstrated Chinese people's strong desire to travel, the nation's robust consumption potential and its economic vitality, thanks to the optimized COVID-19 response management.
(2023-01-28). Nepali envoy hopes Chinese return en masse. ecns.cn Bishnu Pukar Shrestha, the ambassador of Nepal to China, said the Chinese government's adjustment of its COVID-19 response measures is a very important step that helps to promote economic development both for China and the world, enhance people-to-people exchanges and boost tourism.
(2023-01-28). Consumers give economy festive boost. ecns.cn Chinese consumers splurged during the Spring Festival holiday, not only on things like duty-free commodities, jewelry and health-related products, but also on experiences such as travel and entertainment, fueled by the optimization of COVID-19 prevention and control measures, industry experts said.
(2023-01-28). They Say: Fake news attemps to make people forget China's contribution to the global COVID-19 fight. ecns.cn
(2023-01-28). Costa Rica registra 3.805 casos de Covid-19 en la última semana. telesurtv.net De acuerdo a datos del Ministerio de Salud de Costa Rica 16 personas perecieron en la última semana por causas asociadas a la Covid-19.
(2023-01-28). Arriban a Paraguay 100.200 dosis de vacuna contra la Covid-19. telesurtv.net El país registró, del 7 de enero de 2020 al 21 de enero de 2023, 806.256 casos del Sars-Cov-2.
(2023-01-28). Mayo Clinic researchers link ovarian cancer to bacteria colonization in microbiome. newsnetwork.mayoclinic.org ROCHESTER, Minn. — A specific colonization of microbes in the reproductive tract is commonly found in women with ovarian cancer, according to a new study from Mayo Clinic's Center for Individualized Medicine. The discovery, published in Scientific Reports, strengthens evidence that the bacterial component of the microbiome — a community of microorganisms that also consists of viruses, yeasts and fungi — is an important indicator for early detection, diagnosis and prognosis of ovarian cancer. Abigail…
(2023-01-28). [Obituary] Thomas Wilson Meade. thelancet.com Epidemiologist and authority on thrombogenesis and heart disease. He was born in Oxford, UK, on Jan 21, 1936 and died of a lower respiratory tract infection in London, UK, on Oct 24, 2022 aged 86 years.
(2023-01-28). Science Saturday: Removal of both ovaries in younger women associated with increased risk of Parkinson's. newsnetwork.mayoclinic.org Surgical removal of both ovaries is associated with an increased risk of Parkinson's disease and parkinsonism in women younger than 43, Mayo Clinic researchers report in JAMA Network Open. Using health record data from the Rochester Epidemiology Project, the study included 2,750 women who had undergone surgery to remove both ovaries, a procedure called bilateral oophorectomy, and 2,749 who had not. The reasons for the surgery were either a benign (noncancerous) condition — such as endometriosis, cyst, or other reason —…
(2023-01-28). Consumer Health: Why your child's weight matters. newsnetwork.mayoclinic.org Healthy Weight Week will be observed Jan. 15—21, so this is a good time for a reminder of the connection between weight and health during childhood. The prevalence of obesity in adults in the U.S. increased from 30.5% to 41.9% from 1999—2020, according to the Centers for Disease Control and Prevention. The prevalence of severe obesity increased from 4.7% to 9.2% in the same time frame. And the rate of childhood obesity is a serious…
(2023-01-28). Mayo Clinic Minute: Screening for cervical cancer. newsnetwork.mayoclinic.org January is Cervical Cancer Awareness Month in the U.S. The Centers for Disease Control and Prevention notes that more than 12,500 cases of cervical cancer were diagnosed, and more than 4,000 women died from the disease in 2019, the latest year of available data. Dr. Olivia Cardenas-Trowers, a Mayo Clinic urogynecologist, explains the importance of screening for cervical cancer. Watch: The Mayo Clinic Minute youtu.be/qBJBz_D88sg Journalists: Broadcast-quality video (1: 00) is in the downloads at the end of…
(2023-01-28). Mayo Clinic Healthcare expert explains why reflux disease isn't 'just' heartburn. newsnetwork.mayoclinic.org LONDON — Gastroesophageal reflux disease is one of the most common digestive disorders in the world. It happens when acid comes up from the stomach into the esophagus: The stomach can resist acid but the esophagus is less acid-resistant. James East, M.D., a gastroenterologist at Mayo Clinic Healthcare in London, says reflux disease may be common, but there can be severe complications if it is ongoing and left untreated. Heartburn is a key symptom of reflux disease, but…
(2023-01-28). 6 tips to keep your brain healthy. newsnetwork.mayoclinic.org Changes to your body and brain are normal as you age. However, there are some things you can do to help slow any decline in memory and lower your risk of developing Alzheimer's disease or other dementias. Here are six things I recommend to my patients in order of importance: 1. Exercise regularly. Exercise has many known benefits, and regular physical activity also benefits the brain. Multiple research studies show that physical active people are…
(2023-01-28). Mayo Clinic Minute: Role for opioids. newsnetwork.mayoclinic.org Drug overdoses from opioids have been linked to a decreased life span, according to recent data from the Centers for Disease Control and Prevention. The ongoing opioid crisis has been a complicated one for more than a decade. Death rates continue to rise, despite national medical guidelines for prescribing the pain medication. Dr. Holly Geyer leads the opioid stewardship program at Mayo Clinic in Arizona. She says there is an important role for opioids in patient…
(2023-01-28). [Comment] Gaining MOMENTUM against anaemic myelofibrosis. thelancet.com Myelofibrosis is a progressive chronic myeloproliferative neoplasm driven by Janus kinase and signal transducer and activator of transcription (JAK—STAT) pathway activation, mostly due to mutations in JAK2, MPL, and CALR.1 Myelofibrosis arises de novo (primary myelofibrosis) or secondarily from polycythaemia vera and essential thrombocythaemia. Myelofibrosis presents with constitutional symptoms, such as fever, night sweats, and fatigue, accompanied by splenomegaly and either cytopenias or cytoses.
(2023-01-28). [World Report] "Unfettered flow": how ProMED-mail keeps the world alert. thelancet.com For almost 30 years, contributors to ProMED-mail have flagged new and emerging infectious threats to health. Talha Burki reports.
(2023-01-27). For all the Hooplah, Nuclear Fusion won't Save us from Climate Change, and it is Dangerous. juancole.com 
By Joshua Frank | ( Tomdispatch.com ) I awoke on December 13th to news about what could be the most significant scientific breakthrough since the Food and Drug Administration authorized the first Covid vaccine for emergency use two years ago. This time, however, the achievement had nothing to do with that ongoing public …
(2023-01-27). Hong Kong tailors livestream to maintain business. america.cgtn.com The pandemic hit Hong Kong's tailoring industry hard. Many tailors are struggling to stay afloat. Find out how.
(2023-01-27). Crypto Convulsions Reflect Capitalism's Tendency to Breed Instability, w/ Ramaa Vasudevan. youtube.com 
Bitcoin, Stablecoin, Tether, Blockchain, Coinbase, Binance, Etherium, Luna, Celsius, Circle, FTX, NFTs: What's all this crypto jargon really about? What stage of capitalism does it mean we're in? How has digital currency been impacted by the pandemic and the war in Ukraine? What are the geopolitical implications for the US cold war with China? And …
(2023-01-27). Pfizer executive goes thug on James O'Keefe after realizing he had been recorded boasting about 'mutating' Covid virus for profit. americanthinker.com Corporate media blackout of the story but the weirdness is compelling.
(2023-01-27). Chinese people celebrate Spring Festival holiday amid optimized COVID response. ecns.cn Following the downgrading of China's management of COVID-19, people across the country are merrily celebrating the Spring Festival, one of the most important traditional Chinese festivals, with their families.
(2023-01-27). They Say: Some developed countries keep unhappy whether China shifts COVID poliy or not. ecns.cn
(2023-01-27). Antiwar Voices on MLK week; South Africa Power Grid Crisis; US out of Peru; Free Assange! indybay.org On Pacifica: Antiwar Voices on MLK week; South Africa Power Grid Crisis; US out of Peru; Free Assange!
(2023-01-27). What will the Year of the Rabbit bring for China's economy? america.cgtn.com China's economic prospects in 2023 look promising according to Anthony Chan, former Chief Economist at JPMorgan Chase & Co., as the country reopens to the world. "Assuming the number of COVID infections during the new year is manageable," 4.4% growth as the IMF projects …
(2023-01-27). Brasil iniciará nueva campaña de vacunación contra la Covid-19. telesurtv.net El ente prevé iniciar la campaña el 27 de febrero y en una primera fase se inmunizará con el refuerzo bivalente a mayores de 70 años.
(2023-01-27). Presentan vacuna nasal contra la Covid-19 en India. telesurtv.net El fármaco nasal cuenta con la aprobación de la Dirección General de Control de Medicamentos de India.
(2023-01-27). Australian school year commences amid ongoing mass COVID infection, workload crisis, staffing shortages, and record inequality—Build rank-and-file committees to fight for a fully funded public education system! wsws.org Anger and oppositional sentiment must be organised in 2023! The Committee for Public Education urges educators to form rank-and-file committees in your schools.
(2023-01-27). Detectan virus informático capaz de controlar el móvil y robar cuentas bancarias. cubadebate.cu Expertos en ciberseguridad han advertido sobre la proliferación de un nuevo "malware", el cual ataca principalmente a teléfonos Android. Es capaz de tomar el control del móvil por completo en tiempo real e incluso robar las contraseñas de las aplicaciones de cuentas bancarias.
(2023-01-27). Low Enrollment Plagues Many Charter Schools. dissidentvoice.org The mainstream media has long made it seem like parents from coast to coast are frantically clamoring to get their kids into a "limited" number of charter schools. And because there is supposedly not enough space in these charter schools, students are put on a waiting list to get into the school. This neoliberal disinformation …
(2023-01-27). Russian KUB-BLA Suicide Drone Takes Out Ukrainian AN/TPQ-36 Counter-Battery Radar. southfront.org 
Click to see full-size image | On January 27, Russian sources shared footage documenting a strike with a KUB-BLA suicide drone on a Ukrainian American-made AN/TPQ-36 Firefinder counter-battery radar. | The drone strike inflicted heavy damage on the radar, which was reportedly deployed near the settlement of Umanske in the Donetsk People's Republic. | The AN/TPQ-36 was developed to locate the source of artillery, rocket and mortar fire. Kiev forces first received two Firefinder radars after the outbreak of the conflict…